Environmental Law, Governance, and Management- the Need for Environmental Management Systems for Cities

Human activities damage the environment. They deplete natural resources, generate pollution and wastes, accelerate the loss of forests and biological diversity, as well as threaten the water supply. As populations increase, these problems are exacerbated. Cities bear the brunt of increased human activities on limited land space with limited resources. It is therefore essential that cities adopt a system of environmental governance that will help ensure sustainability. As each city has its own mix of geographic, social, economic, political and environmental problems, it would be simplistic to suggest that there is a formula for sustainability that would fit every city. What is clear is that every city needs an effective environmental management system (EMS) to manage its many activities, to ensure that development is controlled, environmental damage is minimized, natural areas are preserved and its citizens have an enhanced quality of life. This paper examines the ingredients for sound environmental management in cities, particularly cities in the developing world. It submits that a sound EMS for a city must first start with sound environmental policies, land use planning and good environmental laws. It emphasizes that the best environmental laws will not work if it is not integrated with sound management policies and implementation, starting with the building of the environmental infrastructure, both physical and institutional. This paper then looks at ISO 14001 certification, in the context of a city and asserts that environmental management systems in their current context, focus largely on resolving problems of pollution. There is a clear lack of ecological dimensions in environmental management systems as exemplified by the ISO 14000 series. This paper submits that environmental stewardship and ecological sustainability is at the heart of sustainable development, and the integration of the natural environment within the city has been largely overlooked. It advocates bringing the natural environment back to our cities and the incorporation of this dimension into environmental management systems. The paper introduces the Singapore Index on Cities\u27 Biodiversity, adopted at the CBD\u27s COP-10 Meeting in Nagoya, Japan, 2010

Extending REDD+ to mangroves and wetlands for small island states and a case study for the conservation of mangroves and inter-tidal mudflats in Singapore

This paper briefly discusses the prospects of using coastal wetlands as REDD+ projects for small island states. The paper contends that the city-state of Singapore would do well to enhance existing laws to more specifically address the challenges and threats faced in conserving mangroves and inter-tidal mudflats, and support their conservation and rehabilitation, not just to facilitate the implementation of REDD+ projects but also to meet other goals like biodiversity conservation and climate change adaptation. The proposal is to expand Sungei Buloh to encompass the mudflats at Kranji which is home to the mangrove horseshoe crab (Carcinoscrorpius rotundicauda); aligned with inter-tidal and coastal management strategies advanced under the auspices of the Ramsar Convention, the Convention on Biological Diversity and the IUCN. However, there are considerable challenges in maintaining an intact eco-system in the face of rapid development, not only in Singapore itself but also in the neighbouring state of Johor, Malaysia. The paper examines the specific legal strategies that will be required to meet the various objectives of conservation in the context of Singapore's laws and the challenges posed by the development plans of both Singapore and Malaysia

Summary proceedings: Workshop on REDD+ and legal regimes of mangroves, peatlands and other wetlands: ASEAN and the world

This report summarises the proceedings of the workshop as interpreted by the assigned rapporteur and editors of the Asia-Pacific Centre for Environmental Law, which were reviewed and approved by the presenters

Association of SARS-CoV-2 clades with clinical, inflammatory and virologic outcomes: An observational study

BACKGROUND: Host determinants of severe coronavirus disease 2019 include advanced age, comorbidities and male sex. Virologic factors may also be important in determining clinical outcome and transmission rates, but limited patient-level data is available. METHODS: We conducted an observational cohort study at seven public hospitals in Singapore. Clinical and laboratory data were collected and compared between individuals infected with different SARS-CoV-2 clades. Firth's logistic regression was used to examine the association between SARS-CoV-2 clade and development of hypoxia, and quasi-Poisson regression to compare transmission rates. Plasma samples were tested for immune mediator levels and the kinetics of viral replication in cell culture were compared. FINDINGS: 319 patients with PCR-confirmed SARS-CoV-2 infection had clinical and virologic data available for analysis. 29 (9%) were infected with clade S, 90 (28%) with clade L/V, 96 (30%) with clade G (containing D614G variant), and 104 (33%) with other clades 'O' were assigned to lineage B.6. After adjusting for age and other covariates, infections with clade S (adjusted odds ratio (aOR) 0·030 (95% confidence intervals (CI): 0·0002-0·29)) or clade O (B·6) (aOR 0·26 (95% CI 0·064-0·93)) were associated with lower odds of developing hypoxia requiring supplemental oxygen compared with clade L/V. Patients infected with clade L/V had more pronounced systemic inflammation with higher concentrations of pro-inflammatory cytokines, chemokines and growth factors. No significant difference in the severity of clade G infections was observed (aOR 0·95 (95% CI: 0·35-2·52). Though viral loads were significantly higher, there was no evidence of increased transmissibility of clade G, and replicative fitness in cell culture was similar for all clades. INTERPRETATION: Infection with clades L/V was associated with increased severity and more systemic release of pro-inflammatory cytokines. Infection with clade G was not associated with changes in severity, and despite higher viral loads there was no evidence of increased transmissibility

A saturated map of common genetic variants associated with human height

Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes(1). Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability. These SNPs are clustered within 7,209 non-overlapping genomic segments with a mean size of around 90 kb, covering about 21% of the genome. The density of independent associations varies across the genome and the regions of increased density are enriched for biologically relevant genes. In out-of-sample estimation and prediction, the 12,111 SNPs (or all SNPs in the HapMap 3 panel(2)) account for 40% (45%) of phenotypic variance in populations of European ancestry but only around 10-20% (14-24%) in populations of other ancestries. Effect sizes, associated regions and gene prioritization are similar across ancestries, indicating that reduced prediction accuracy is likely to be explained by linkage disequilibrium and differences in allele frequency within associated regions. Finally, we show that the relevant biological pathways are detectable with smaller sample sizes than are needed to implicate causal genes and variants. Overall, this study provides a comprehensive map of specific genomic regions that contain the vast majority of common height-associated variants. Although this map is saturated for populations of European ancestry, further research is needed to achieve equivalent saturation in other ancestries.A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants

A saturated map of common genetic variants associated with human height.

Common single-nucleotide polymorphisms (SNPs) are predicted to collectively explain 40-50% of phenotypic variation in human height, but identifying the specific variants and associated regions requires huge sample sizes1. Here, using data from a genome-wide association study of 5.4 million individuals of diverse ancestries, we show that 12,111 independent SNPs that are significantly associated with height account for nearly all of the common SNP-based heritability. These SNPs are clustered within 7,209 non-overlapping genomic segments with a mean size of around 90 kb, covering about 21% of the genome. The density of independent associations varies across the genome and the regions of increased density are enriched for biologically relevant genes. In out-of-sample estimation and prediction, the 12,111 SNPs (or all SNPs in the HapMap 3 panel2) account for 40% (45%) of phenotypic variance in populations of European ancestry but only around 10-20% (14-24%) in populations of other ancestries. Effect sizes, associated regions and gene prioritization are similar across ancestries, indicating that reduced prediction accuracy is likely to be explained by linkage disequilibrium and differences in allele frequency within associated regions. Finally, we show that the relevant biological pathways are detectable with smaller sample sizes than are needed to implicate causal genes and variants. Overall, this study provides a comprehensive map of specific genomic regions that contain the vast majority of common height-associated variants. Although this map is saturated for populations of European ancestry, further research is needed to achieve equivalent saturation in other ancestries

Public Housing in Singapore: A Success Story in Sustainable Development

The Impact of Environmental Law - Stories of the World We Want128-154USAIUCN Academy of Environmental Law Serie

WILDLIFE TRADE IN CHINA AND VIETNAM: A COMPARATIVE STUDY OF THE IMPLEMENTATION OF THE CONVENTION ON INTERNATIONAL TRADE IN ENDANGERED SPECIES OF WILD FAUNA AND FLORA(CITES)

10.1142/9789813230620_0002Sustainability Matters625-57SingaporeSustainability Matters, published by World Scientifi

Beyond Kyoto : climate change including a discussion of the AP6 initiative from the Australian perspective

This paper presents an overview of the Australia Commonwealth government’s response to the challenges of climate change, that has been very much tempered by concerns over the adverse impact that any such response may have on the Australian economy. It focuses in particular on the establishment of the Asia Pacific Partnership on Clean Development and Climate (commonly referred to as the AP6 initiative) and discusses Australia’s options within a regional framework